Preparation
Our staff conducts comprehensive psychiatric assessment and establishes therapeutic intentions for your session.

Rapid Relief for Treatment-Resistant Mental Health Conditions

Understanding Treatment Resistance
If you've tried medication, therapy, or both and you're still struggling to find relief, you're not alone, and it's not because you haven't tried hard enough. Finding the right treatment often means trying different options, adjusting course, and living with uncertainty while you wait to see what helps. In the meantime, it's exhausting when symptoms keep showing up in your relationships, your work, and the way you move through daily life.
Ketamine infusion therapy takes a different approach. Rather than working through the same pathways as traditional antidepressants, it works with your brain's natural ability to form new connections. When combined with integration therapy, it can help you process difficult experiences, see things from a new perspective, and build coping tools that actually work.

The Science Behind the Treatment
Ketamine therapy is a medically supervised treatment using low-dose ketamine, an FDA-approved anesthetic, to reduce symptoms of depression, PTSD, anxiety, and chronic pain while supporting therapeutic insight. Ketamine has been used safely in medical settings for over 50 years and is included on the WHO List of Essential Medicines.
Ketamine works differently than traditional antidepressants. Instead of targeting serotonin, it interacts with glutamate, one of the brain's key messengers. This can help "unstick" thought patterns that have felt stuck for a long time, encouraging your brain to build new, healthier connections. It also boosts a protein called BDNF, which supports this process of growth and change.
During your session, you'll recline comfortably in a therapeutic setting while our team administers ketamine via intramuscular injection or IV infusion. You'll experience altered consciousness - a dissociative state that may include visual imagery, emotional insights, and a sense of separation from ordinary concerns. Our staff member remains with you throughout, providing grounding support and therapeutic guidance. Sessions last approximately 2 hours, including the dissociative experience and integration work to process insights.
Many people start noticing a difference within hours or days of their very first session. That said, everyone's journey is different. Ketamine treatment typically begins with a series of 6 sessions over a few weeks to give the treatment the best chance to take hold. From there, your care team will work with you to figure out what ongoing support looks like, based on how you're responding and how you're feeling.
Rapid, Transformative Relief

Ketamine targets glutamate rather than serotonin, offering an alternative treatment path compared to conventional medications
Some patients notice improvement in mood or symptoms within hours to days
Sessions are often combined with talk therapy to help process insights and integrate the experience
Research suggests ketamine may promote formation of new neural connections, potentially helping "rewire" patterns tied to depression
Administered and monitored by trained clinicians in a controlled setting for safety
Dosing, frequency, and format (IV or IM) is adjusted based on patient response
Most patients can resume normal activities the same day of treatment
Compare Your Options
| Treatment | Mechanism | Time | Results | Duration | Downtime | Best For |
|---|---|---|---|---|---|---|
| Ketamine Therapy | NMDA receptor modulation | 2 hours | Varies | Individualized | Minimal | Treatment-resistant conditions |
| Traditional Antidepressants | Neurotransmitter modulation | Daily | Varies | Ongoing | None | First-line treatment |
| Exomind TMS Therapy | Magnetic stimulation | 20 - 30 min/session | Varies | Multi-session | None | Non-invasive depression treatment |

Finding Your Path to Healing
Ketamine therapy may be appropriate for individuals with persistent symptoms who have not responded to standard care.
You should avoid ketamine therapy if you:
A comprehensive psychiatric and medical evaluation is required before beginning treatment to ensure safety and appropriateness.
Know what to expect before your ketamine session:
Our staff conducts comprehensive psychiatric assessment and establishes therapeutic intentions for your session.
You'll recline in a comfortable, private therapeutic space with soft lighting, eye shades, and curated music to support your journey.
Our team administers ketamine via IM injection or IV infusion.
During your approximately 2-hour session, you will experience the benefits of ketamine therapy while your vitals are continuously monitored by a trained clinician.
Following the session, therapeutic support and integration work is available to help anchor insights and develop actionable therapeutic strategies.

What to Know
During ketamine-assisted therapy, you may experience dissociation (a sense of detachment from your body), visual or auditory perceptual changes, emotional intensity, nausea (can be managed with anti-nausea medication), and temporary increases in blood pressure and heart rate. These effects are expected during treatment and are continuously monitored by clinical staff. Ketamine side effects typically resolve during the recovery period after the session.
Following treatment, some patients may experience mild fatigue, headache, or emotional sensitivity for a variable period after the session, most commonly within the same day. In rare cases, patients may experience emotionally intense or challenging psychological content during the session. When this occurs, our trained clinical staff provide structured therapeutic support to ensure the experience remains safe and supported.
Ketamine was FDA-approved as an anesthetic in 1970 and has over 50 years of established medical use. While ketamine is used off-label for psychiatric conditions, all treatments are administered under medical supervision with continuous monitoring throughout the session. Vital signs, including cardiovascular measures, are tracked to ensure safety, particularly for individuals with controlled hypertension. Our team provides specialized clinical oversight in ketamine-assisted therapy. Patients are evaluated before treatment to determine appropriateness based on medical and psychiatric history, including screening for factors such as cardiovascular risk and substance use history.
Ketamine therapy in Ponte Vedra typically ranges from $550-$600 per session, depending on administration method (IM vs IV), session length, and level of therapeutic support. Most patients complete an initial series of 6 sessions over 2-4 weeks, followed by monthly maintenance sessions. Factors affecting cost include medical monitoring requirements, integration therapy sessions, and whether treatment is combined with other modalities like psychotherapy or neurofeedback. Exact pricing will be discussed during your consultation based on your individual treatment plan.
Note that ketamine therapy is a self-pay service, with discounted rates provided when purchasing 6 session bundles upfront. We can provide superbills upon request that you may submit to your insurance for potential out-of-network reimbursement. We also accept patient-applied Advance Care financing as well as HSA and FSA funds.

Serving Patients across Jacksonville, Jacksonville Beach, St. Johns, Nocatee, St. Augustine, & Surrounding Northeast Florida Communities
Trained clinical experts specializing in ketamine treatments
Our team's expertise in therapeutic integration maximizes lasting change
Continuous monitoring with PA-C clinical supervision
Combines ketamine-assisted therapy with comprehensive psychiatric care
Discover complementary therapies designed to work alongside your ketamine treatment plan for optimal results.
Therapy, counseling, and holistic approaches for lasting emotional wellness
Non-invasive neurofeedback, brain mapping, and TMS for optimal brain health
Your Questions Answered
Ketamine has been used safely in medical settings for over 50 years and is included on the WHO List of Essential Medicines. Ketamine therapy is a medically supervised treatment that combines low-dose ketamine, an FDA-approved anesthetic, with therapeutic support and integration work. Unlike ketamine infusions alone, this approach uses the altered, dissociative experience as a catalyst for psychological healing and transformation, with trained therapists guiding the session and helping you process insights afterward.
Ketamine was FDA approved as an anesthetic in 1970 and has more than 50 years of established medical use. While ketamine is used off label for psychiatric conditions, all treatments are administered under medical supervision with continuous monitoring throughout the session. Vital signs, including cardiovascular measures, are tracked to ensure safety, particularly for individuals with controlled hypertension.
Our team provides specialized clinical oversight in ketamine-assisted therapy. Patients are evaluated before treatment to determine appropriateness based on medical and psychiatric history, including screening for factors such as cardiovascular risk and substance use history.
Most patients complete 6 sessions over 2-4 weeks for the initial series, with symptom relief often beginning after 1-2 treatments. Maintenance sessions are typically scheduled monthly or every 4-6 weeks to sustain benefits. Your treatment plan will be personalized based on your response.
Ketamine therapy in Ponte Vedra typically ranges from $550-$600 per session, depending on administration method (IM vs IV), session length, and level of therapeutic support. Most patients complete an initial series of 6 sessions over 2-4 weeks, followed by monthly maintenance sessions. Exact pricing will be discussed during your consultation based on your individual treatment plan.
Ketamine therapy is most effective for treatment-resistant depression, PTSD, anxiety disorders, OCD, and chronic pain syndromes. It's particularly valuable when traditional antidepressants and therapy haven't provided adequate relief.
During each 2-hour session, you'll feel dissociated from ordinary reality, a dreamlike state with altered perception, emotional insights, and sometimes visual imagery. The experience is deeply personal and varies between individuals and sessions. Your provider remains with you throughout the session to provide grounding and support.
Ketamine therapy produces a temporary altered, dissociative state of consciousness, but the goal is therapeutic healing, not recreation.
Ketamine therapy for depression and other psychiatric conditions is typically not covered by insurance as it's off-label use. However, we provide documentation for out-of-network reimbursement.